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Inventi Impact: Molecular Modeling

Articles

  • Inventi:pmm/31404/20
    Identification of the Fipronil Resistance Associated Mutations in Nilaparvata lugens GABA Receptors by Molecular Modeling
    Research 2020 : April - June
    Yafeng Tian, Ya Gao, Yanming Chen, Genyan Liu, Xiulian Ju

    Fipronil, as the first commercialized member of phenylpyrazole insecticides, has been\nwidely used to control planthoppers in China due to its high insecticidal activity and low toxicity\nto mammals. However, insects have developed resistance to phenylpyrazoles after their long-term\nuse. The resistance mechanism of insects to fipronil has not been well identified, which limited the\ndevelopment of phenylpyrazole insecticides. In the present study, we aimed to elucidate the related\nfipronil-resistance mechanism in N. lugensGABAreceptors by homology modeling, molecular docking,\nand molecular dynamics. ..........................

    How to Cite this Article
    Attribution/ CC Compliant Citation: Tian, Yafeng, et al. \"Identification of The Fipronil Resistance Associated Mutations in\nNilaparvata lugens GABA Receptors by Molecular Modeling.\" Molecules 24.22 (2019): 4116.\nhttps://doi:10.3390/molecules24224116\nhttp://creativecommons.org/licenses/by/4.0/\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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